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A History of Firsts

Yale has a history of contributions to the field of medicine that have had a major impact on the health of people around the world. Some of these are: 

1896

Arthur Wright produces first X-ray

1942

Introduction of life-saving penicillin to the United States

1942

First use of chemotherapy as a cancer treatment in the U.S.

1946

First U.S. hospital to allow healthy newborns to say in rooms with mother.

1947

Yale-New Haven Hospital opens the first rheumatic fever-cardiac clinic, one of the nation's first regional heart centers

1949

Developed first artificial heart pump in the U.S.

1949

First U.S. hospital to introduce natural childbirth as a general service

1957

First hospital to use fetal heart monitoring

1958

Discovery of melatonin

1959

First antiviral drug developed

1960

World's first intensive care unit for newborns

1966

Phrenic nerve pacemaker allows quadriplegics to breathe without a respirator

1966

"Morning-After" birth control pill developed

1972

First hospital-based newborn screening program for sickle cell anemia in the U.S.

1975

Lyme disease identified and named

1978

FDA approved timolol to treat glaucoma, the first effective therapy for the disease since the early 1900s

1979

First insulin pump for diabetes

1980

The first genetically modified mouse (these are now used in the early stages of research to develop treatment for diseases

1985

First fetal cardiovascular center in the U.S.

1994

FDA approved Zerit, a drug to treat HIV and part of the three-drug “cocktail” that extended the lives of many tens of thousands of people with HIV/AIDS worldwide

1997

The discovery of a mechanism of protein folding, a step toward understanding neurodegenerative conditions such as Alzheimer's disease

1997

First documented heart transplants of adult identical twins, one in 1992, second in 1997

2010

First to use high-throughput DNA sequencing to diagnose a disease

2014

Genomic analysis leads to the discovery, diagnosis, and treatment of a rare disease